1. Gilead has increased its research and development (R&D) spending by 25% in Q1, reaching over $1.4 billion.
2. Gilead's CFO, Andrew Dickinson, aims for the share of revenue allocated to R&D to be in the low-20% range.
4. Dickinson expects the company's operating margin to strengthen over time as it progresses through its current phase 3 trials.
8. The company has also invested in TIGIT, an immuno-oncology target, with more data expected from an ongoing phase 2 trial in the first half of the year.
9. Gilead reported promising results in December 2022, showing a combination of domvanalimab and Arcus' anti-PD1 zimberelimab reduced the risk of disease progression by 45% compared to zimberelimab alone.
10. More mature data from a larger patient population is expected to be presented later this quarter, according to Gilead's Chief Medical Officer, Merdad Parsey.