Myelin associated glycoprotein (MAG) is a component of myelin with a MW of 100kDA. The IgM antibody can be demonstrated in both the central and peripheral nerves.

Clinical feature of peripheral neuropathy are seen.

MAG antibody can associated with Waldenstrom’s macroglobulinaemia and multiplr myelomas.

Image: primate sciatic nerve showing staining of the periaxonal regions.