Rodent stomach stained with mitochondrial antibody | Mitochondrial antibody: rodent liver | Mitochondrial antibody: stomach | ||
Stomach | Liver | Kidney tubules | ||
Parietal cells | Chief cells | Hepatocytes | Proximal | Distal |
++ | +/– | ++ | ++ | +++ |
Rodent stomach: Cytoplasm of gastric parietal cells is shown in green with black unstained nuclei. | Rodent liver showing granular staining of the cytoplasm with red nuclei. | In contrast to the LKM antibody, AMA stains cytoplasm of both the proximal and distal renal tubules. Centre is unstained glomerulus. | ||
Anti-mitochondrial antibodies are strongly associated with Primary biliary cirrohsis. |